Left atrial appendage thrombi despite oral anticoagulation in transthyretin amyloid cardiomyopathy patients undergoing electrical cardioversion for atrial fibrillation or − flutter
A high rate of left atrial appendage thrombus was observed in ATTR-CM, leading to DCCV cancellation in 20.5% of patients. Despite a high immediate success rate (92.3%), sustained sinus rhythm control was achieved in only 62.8% following DCCV. These findings advise using TEE or CT prior to DCCV to exclude LAAT in ATTR-CM patients, even in those with oral anticoagulation.
Authors
- Nikita Ermolaev
- Roza Badr Eslam (ORCID: https://orcid.org/0000-0002-0360-2360)
- Robin Willixhofer (ORCID: https://orcid.org/0000-0003-3405-5715)
- Stefan Kastl (ORCID: https://orcid.org/0000-0002-9682-0200)
- Andreas Kammerlander (ORCID: https://orcid.org/0000-0002-3061-5570)
- Johannes Kästner (ORCID: https://orcid.org/0000-0001-6178-7669)
- Franz Duca (ORCID: https://orcid.org/0000-0002-7519-5274)
- Senta Graf (ORCID: https://orcid.org/0000-0002-4443-8667)
- Mahshid Eslami
- Luciana Camuz Ligios
- Michael Poledniczek (ORCID: https://orcid.org/0000-0002-6091-9823)
- Jutta K Bergler-Klein (ORCID: https://orcid.org/0000-0003-2591-1380)
- Christina Kronberger (ORCID: https://orcid.org/0000-0002-3866-3710)
- René Rettl (ORCID: https://orcid.org/0000-0001-6409-5158)
- Bernhard Gregshammer
- Luca List
- Christian Hengstenberg
- Christian Nitsche
- Christina Binder
Institutions
- Medical University of Vienna (AT)
Publication Details
- Journal
- IJC Heart & Vasculature
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1016/j.ijcha.2025.101790
- Citations
- 1
- Primary Topic
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.81