Increased dipeptidyl peptidase 4 in patients with concomitant transthyretin cardiac amyloidosis and severe aortic stenosis
Our findings suggest that DPP4 may be a marker of ATTR-CM in patients with severe AS. In all AS patients, those with and without coexisting ATTR-CM, high DPP4 levels were asociated with better cardiac function.
Authors
- Pål Aukrust
- Margrethe Flesvig Holt (ORCID: https://orcid.org/0000-0003-3320-2808)
- Anders Hodt
- Kaspar Broch (ORCID: https://orcid.org/0000-0003-4316-805X)
- Kristoffer Russell (ORCID: https://orcid.org/0000-0002-1374-4805)
- Lars Gullestad
- Sophie Foss Kløve
- Thor Ueland
- Annika E. Michelsen
- Jan Otto Beitnes
- A. Fló
Institutions
- Oslo University Hospital (NO)
- University Hospital of North Norway (NO)
- University of Oslo (NO)
Publication Details
- Journal
- IJC Heart & Vasculature
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1016/j.ijcha.2025.101820
- Primary Topic
- Peptidase Inhibition and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00