The Use of Proton Radiation in the Management of Adenoid Cystic Carcinoma
Proton therapy for ACC of the head and neck yields excellent locoregional control, particularly in the adjuvant setting, with manageable toxicity. For patients with unresectable disease or those seeking organ preservation, definitive proton therapy remains a viable, durable treatment option. These findings support proton therapy as a preferred modality in head and neck ACC.
Authors
- Sean Matthew McBride (ORCID: https://orcid.org/0000-0002-9676-1669)
- Daphna Y. Gelblum (ORCID: https://orcid.org/0000-0001-7211-6246)
- Kaveh Zakeri (ORCID: https://orcid.org/0000-0003-3921-480X)
- Nadeem Riaz (ORCID: https://orcid.org/0000-0001-9873-5862)
- Nicolas Toumbacaris
- Yao Yu (ORCID: https://orcid.org/0000-0002-2814-4482)
- Alan Loh Ho (ORCID: https://orcid.org/0000-0002-6885-3742)
- Irini Yacoub
- Lara Ann Dunn (ORCID: https://orcid.org/0000-0001-5318-2571)
- Nancy Y. Lee (ORCID: https://orcid.org/0000-0003-3044-9522)
- Eric Jeffrey Sherman (ORCID: https://orcid.org/0000-0002-4960-4783)
- Marc A. Cohen (ORCID: https://orcid.org/0000-0002-6104-7967)
- Nader Mohamed (ORCID: https://orcid.org/0000-0001-9877-5717)
- Ian Ganly (ORCID: https://orcid.org/0000-0001-7636-5426)
- Achraf A. Shamseddine (ORCID: https://orcid.org/0000-0003-3686-5850)
- Richard Wong (ORCID: https://orcid.org/0000-0002-8040-7083)
- Daniel Kallini
- Zhigang Zhang (ORCID: https://orcid.org/0000-0002-4974-5850)
- Linda Chen (ORCID: https://orcid.org/0000-0001-7078-163X)
- Loren S. Michel
Institutions
- Memorial Sloan Kettering Cancer Center (US)
- New York Proton Center (US)
- Rowan University (US)
- New York University (US)
Publication Details
- Journal
- International Journal of Particle Therapy
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1016/j.ijpt.2025.101206
- Citations
- 1
- Primary Topic
- Salivary Gland Tumors Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.01