A molecular census to elucidate the demixing mechanism of membraneless organelles
We introduce a computational by-the-numbers approach to benchmark different demixing models that may explain the assembly of membraneless organelles. Our results suggest that cells use different mechanisms to form subnuclear organelles with different biophysical properties.
Authors
- Fernando Muzzopappa (ORCID: https://orcid.org/0000-0001-6420-828X)
- Carine Ali (ORCID: https://orcid.org/0000-0001-8007-7910)
- Fabian Erdel (ORCID: https://orcid.org/0000-0003-2888-7777)
Institutions
- Centre National de la Recherche Scientifique (FR)
- Université Fédérale de Toulouse Midi-Pyrénées (FR)
Publication Details
- Journal
- Genome biology
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1186/s13059-025-03806-0
- Citations
- 2
- Primary Topic
- RNA Research and Splicing
- Type
- article
- Field-Weighted Citation Impact
- 1.61