Pan-Asian adapted ESMO Clinical Practice Guidelines for the diagnosis, treatment and follow-up of patients with pancreatic cancer
The European Society for Medical Oncology (ESMO) Clinical Practice Guidelines for the diagnosis, treatment and follow-up of patients with pancreatic cancer, published in November 2023, were adapted in December 2024, according to previously established standard methodology, to produce the Pan-Asian adapted (PAGA) ESMO consensus guidelines for the management of Asian patients with pancreatic cancer. The adapted guidelines presented in this manuscript represent the consensus opinions reached by a panel of Asian experts in the treatment of patients with pancreatic cancer representing the oncological societies of China (CSCO), Indonesia (ISHMO), India (ISMPO), Japan (JSMO), Korea (KSMO), Malaysia (MOS), the Philippines (PSMO), Singapore (SSO), Taiwan (TOS) and Thailand (TSCO), co-ordinated by ESMO and the Singapore Society of Oncology (SSO). The voting was based on scientific evidence and was independent of the current treatment practices, drug access restrictions and reimbursement decisions in the different regions of Asia. The latter are discussed separately in the manuscript. The aim is to provide guidance for the optimisation and harmonisation of the management of patients with pancreatic cancer across the different countries of Asia, drawing on the evidence provided by both Western and Asian trials. Attention is drawn to the disparity in drug approvals and reimbursement strategies between the different countries.
Authors
- Indra Wijaya (ORCID: https://orcid.org/0000-0002-9446-2307)
- Suebpong Tanasanvimon (ORCID: https://orcid.org/0000-0002-3904-4719)
- C.E. Chee
- George E. Pentheroudakis (ORCID: https://orcid.org/0000-0002-6632-2462)
- Shailesh Bondarde
- Thierry Conroy (ORCID: https://orcid.org/0000-0001-7548-284X)
- Krittiya Korphaisarn (ORCID: https://orcid.org/0000-0001-5739-0175)
- Myung Ah Lee (ORCID: https://orcid.org/0000-0002-1204-0574)
- Wen‐Chi Chou (ORCID: https://orcid.org/0000-0002-0361-4548)
- Glenn Kunnath Bonney (ORCID: https://orcid.org/0000-0002-9034-3255)
- Jens Samol (ORCID: https://orcid.org/0000-0001-6109-3528)
- Hei‐Cheul Jeung (ORCID: https://orcid.org/0000-0003-0952-3679)
- Akihiro Ohba (ORCID: https://orcid.org/0000-0002-9153-3798)
- Makoto Ueno (ORCID: https://orcid.org/0000-0003-4480-0029)
- Takayuki Yoshino (ORCID: https://orcid.org/0000-0002-0489-4756)
- Joycelyn Jie Xin Lee (ORCID: https://orcid.org/0000-0002-1070-6125)
- Elizabeth Smyth (ORCID: https://orcid.org/0000-0002-4667-1817)
- Michel Ducreux (ORCID: https://orcid.org/0000-0001-8649-7449)
- Chunyi Hao (ORCID: https://orcid.org/0000-0002-1233-1689)
- Cosmas Rinaldi Adithya Lesmana (ORCID: https://orcid.org/0000-0001-9992-9968)
- SushilK Aggarwal
- David Tai (ORCID: https://orcid.org/0000-0002-2612-0065)
- Andrés Cervantes (ORCID: https://orcid.org/0000-0003-3806-3691)
- Nur Fa’izah Ab Muin (ORCID: https://orcid.org/0000-0001-9755-8032)
- Lei Wang (ORCID: https://orcid.org/0000-0002-5071-5800)
- Bing Jia (ORCID: https://orcid.org/0000-0002-6560-3991)
- Li‐Tzong Chen (ORCID: https://orcid.org/0000-0003-3250-7167)
- Najihah Mohd Hashim (ORCID: https://orcid.org/0000-0003-1133-7998)
- Eileen Poon (ORCID: https://orcid.org/0000-0001-9452-3408)
- E Cargullo
Institutions
- Memorial Hospital of South Bend (US)
- Siriraj Hospital (TH)
- Johns Hopkins University (US)
- Kaohsiung Medical University (TW)
- Inserm (FR)
- SingHealth (SG)
- Nanyang Technological University (SG)
- Chang Gung University (TW)
- Yonsei University (KR)
- Peking University (CN)
- Mahidol University (TH)
- Université Paris-Saclay (FR)
- University of Perpetual Help System DALTA (PH)
- European Society for Medical Oncology (CH)
- Renji Hospital (CN)
- Churchill Hospital (GB)
- Institut Gustave Roussy (FR)
- King Chulalongkorn Memorial Hospital (TH)
- Tan Tock Seng Hospital (SG)
- University of Indonesia (ID)
- Kanagawa Prefectural Hospital Organization (JP)
- Sultan Ismail Specialist Hospital (MY)
- Dr. Hasan Sadikin General Hospital (ID)
- Shizuoka Cancer Center (JP)
- Peking University Cancer Hospital (CN)
- Institut de Cancérologie de Lorraine (FR)
- National University Cancer Institute, Singapore (SG)
- Sir Ganga Ram Hospital (IN)
- Linkou Chang Gung Memorial Hospital (TW)
- National Cancer Centre Singapore (SG)
- Indian Numismatic, Historical and Cultural Research Foundation (IN)
- Gangnam Severance Hospital (KR)
- National Cancer Center Hospital East (JP)
- National University Health System (SG)
- Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo (ID)
- INCLIVA Health Research Institute (ES)
- The Catholic University of Korea Seoul St. Mary's Hospital (KR)
- Kanagawa Cancer Center
- Interdisciplinarité en Santé Publique Interventions et Instruments de mesure complexes – Région Est (FR)
- Catholic University of Korea (KR)
- National University of Malaysia (MY)
- Padjadjaran University (ID)
Publication Details
- Journal
- ESMO Open
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1016/j.esmoop.2025.105826
- Citations
- 3
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 3.14