Safety and immunogenicity of a homologous booster dose of a SARS-CoV-2 recombinant protein nanoparticle vaccine (GBP510) adjuvanted with AS03: 12 months follow-up result of an open-label, nonrandomized extension of a phase 1/2 trial
A homologous GBP510/AS03 booster was well tolerated and induced robust, durable neutralizing antibody responses against SARS-CoV-2, including Omicron variant.
Authors
- Joong Sik Eom (ORCID: https://orcid.org/0000-0003-2744-1159)
- Francesca Solmi
- Hee Jin Cheong (ORCID: https://orcid.org/0000-0002-2532-1463)
- Ki Tae Kwon (ORCID: https://orcid.org/0000-0003-4666-0672)
- Yoonyeong Lee (ORCID: https://orcid.org/0000-0002-1587-4961)
- Kyung Hwa Park (ORCID: https://orcid.org/0000-0003-2836-6963)
- Neil P. King (ORCID: https://orcid.org/0000-0002-2978-4692)
- Su Jeen Lee
- Hee Jung Choi (ORCID: https://orcid.org/0000-0002-1468-4074)
- Dong Sik Jung (ORCID: https://orcid.org/0000-0003-3881-9073)
- Marguerite Koutsoukos (ORCID: https://orcid.org/0000-0002-4174-8424)
- Young Rong Kim (ORCID: https://orcid.org/0000-0001-9422-4440)
- Ho Keun Park
- Jang Wook Sohn (ORCID: https://orcid.org/0000-0003-4792-0456)
- Maria Angeles Ceregido (ORCID: https://orcid.org/0009-0004-5412-2641)
- Won Suk Choi (ORCID: https://orcid.org/0000-0001-5874-4764)
- Jung Yeon Heo (ORCID: https://orcid.org/0000-0002-6548-1939)
- Joon Young Song (ORCID: https://orcid.org/0000-0002-0148-7194)
- Shin‐Woo Kim (ORCID: https://orcid.org/0000-0002-3755-8249)
- Su Jin Jeong (ORCID: https://orcid.org/0000-0003-4025-4542)
- David Veesler (ORCID: https://orcid.org/0000-0002-6019-8675)
- Hun Kim (ORCID: https://orcid.org/0000-0003-3726-7094)
- Jacob Lee (ORCID: https://orcid.org/0000-0002-7041-065X)
- Jin Soo Lee (ORCID: https://orcid.org/0000-0001-7862-5519)
- Young Keun Kim (ORCID: https://orcid.org/0000-0002-2120-6265)
- Ji Hwa Ryu (ORCID: https://orcid.org/0000-0002-3033-1180)
- Yong Wook Park
Institutions
- Chonnam National University (KR)
- Gachon University (KR)
- Ewha Womans University (KR)
- Hallym University (KR)
- Inha University (KR)
- University of Wah (PK)
- Yonsei University (KR)
- Korea University (KR)
- University of Washington (US)
- Severance Hospital (KR)
- Korea University Medical Center (KR)
- Kyungpook National University Hospital (KR)
- Ansan University (KR)
- Gachon University Gil Medical Center (KR)
- Chonnam National University Hospital (KR)
- GlaxoSmithKline (Belgium) (BE)
- Wonju Severance Christian Hospital (KR)
- Gangnam Severance Hospital (KR)
- Korea University (JP)
- Dong-A University (KR)
- Ajou University (KR)
- Korea Research Institute of Bioscience and Biotechnology (KR)
Publication Details
- Journal
- International Journal of Infectious Diseases
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1016/j.ijid.2025.108108
- Citations
- 1
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 1.40