Longitudinal cardiovascular magnetic resonance evaluation of progressive pressure overload due to O-ring induced ascending aortic constriction in rats
This animal model mimics the gradual progression of stenosis seen in humans, highlighting its translational potential. Early LA diameter predicted myocardial fibrosis. These findings underscore the model's relevance for studying disease progression in LV pressure overload.
Authors
- Ida Marie Hauge‐Iversen (ORCID: https://orcid.org/0000-0002-2839-1061)
- Einar S Nordén
- Emil Knut Stenersen Espe (ORCID: https://orcid.org/0000-0001-8500-4921)
- Ivar Sjaastad (ORCID: https://orcid.org/0000-0002-0131-2036)
- Arne Olav Melleby (ORCID: https://orcid.org/0000-0002-3524-8829)
- Lili Zhang (ORCID: https://orcid.org/0000-0002-9341-5832)
Institutions
- Oslo University Hospital (NO)
- University of Oslo (NO)
- Institutt for Eksperimentell Medisinsk Forskning (NO)
Publication Details
- Journal
- Journal of Cardiovascular Magnetic Resonance
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1016/j.jocmr.2025.101969
- Primary Topic
- Cardiovascular Function and Risk Factors
- Type
- article
- Field-Weighted Citation Impact
- 0.00