Real‐Time Monitoring of DNA Origami‐Cell Interactions via Single Particle Tracking (Small 40/2025)
DNA Origami In article number 2502496, Tania Patiño Padial and co-workers highlights real-time single-particle tracking of ligand-functionalized DNA origami nanorods interacting with cell membranes. Leveraging the spatial programmability of DNA origami, this approach enables precise interrogation of receptor-ligand binding kinetics and dynamics at the cell surface, offering new insights into nanoscale biointerfaces with high spatial and temporal resolution.
Authors
- Tania Patiño (ORCID: https://orcid.org/0000-0001-9979-7926)
- Roger R. Brillas (ORCID: https://orcid.org/0000-0001-9406-597X)
- Tom F. A. de Greef (ORCID: https://orcid.org/0000-0002-9338-284X)
- Indra Van Zundert (ORCID: https://orcid.org/0000-0002-9975-6902)
- Lorenzo Albertazzi (ORCID: https://orcid.org/0000-0002-6837-0812)
- Angelina Yurchenko (ORCID: https://orcid.org/0000-0003-2378-009X)
- Alessandro Bertucci (ORCID: https://orcid.org/0000-0003-4842-9909)
- Lars J. M. M. Paffen (ORCID: https://orcid.org/0009-0002-0218-6403)
- Elena Spezzani (ORCID: https://orcid.org/0009-0008-0533-1374)
Institutions
- University of Parma (IT)
- Biosensor (Italy) (IT)
- Eindhoven University of Technology (NL)
Publication Details
- Journal
- Small
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1002/smll.70742
- Primary Topic
- Advanced biosensing and bioanalysis techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00