Polyglycerol‐Grafted Graphene Oxide with pH‐Responsive Charge‐Convertible Surface to Dynamically Control the Nanobiointeractions for Enhanced in Vivo Tumor Internalization (Small 40/2025)
Cancer Theranostics In article number 2503029, Yajuan Zou, Alberto Bianco, and Yuta Nishina reveal that the in vivo fate of polyglycerol-grafted graphene oxide with pH-responsive charge-convertible surface depends on the density of the functional groups. Controlling the amounts of these functional groups allowed to achieve prolonged circulation and enhanced tumor cellular internalization. These findings will advance the design of pH-responsive nanomaterials for precise cancer theranostics.
Authors
- Yuta Nishina (ORCID: https://orcid.org/0000-0002-4958-1753)
- Alberto Bianco (ORCID: https://orcid.org/0000-0002-1090-296X)
- Yajuan Zou (ORCID: https://orcid.org/0000-0001-7178-3899)
Institutions
- Centre National de la Recherche Scientifique (FR)
- Okayama University (JP)
- Université de Strasbourg (FR)
Publication Details
- Journal
- Small
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1002/smll.70739
- Citations
- 1
- Primary Topic
- Graphene and Nanomaterials Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.67