Efficiency of Gla-300 versus Gla-100 Across Age Groups in People Living with Type 2 Diabetes in France: A Post Hoc Analysis of an Observational Longitudinal Study

This EF-BI post hoc analysis found that Gla-300 was associated with lower overall costs, better persistence, and fewer insulin-related acute events compared to Gla-100 in several age subgroups in people with T2D in France. Further investigations are needed to confirm these results, including glycemic control and comparison with other second-generation basal insulins.

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Publication Details

Journal
Advances in Therapy
Published
2025-10-09
DOI
https://doi.org/10.1007/s12325-025-03381-7
Primary Topic
Diabetes Treatment and Management
Type
article
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article

Efficiency of Gla-300 versus Gla-100 Across Age Groups in People Living with Type 2 Diabetes in France: A Post Hoc Analysis of an Observational Longitudinal Study

Alfred Penfornis, Olivier Hanon, N. Allali, B. Detournay et al.
Advances in Therapy
Diabetes Treatment and Management
article

Efficiency of Gla-300 versus Gla-100 Across Age Groups in People Living with Type 2 Diabetes in France: A Post Hoc Analysis of an Observational Longitudinal Study

Alfred Penfornis, Olivier Hanon, N. Allali, B. Detournay, Pierre Gourdy, Corinne Emery, Isabelle Borget, I. Bureau, Pierre Évenou, Patrice Darmon, Aymeric Mahieu
article en

Abstract

This EF-BI post hoc analysis found that Gla-300 was associated with lower overall costs, better persistence, and fewer insulin-related acute events compared to Gla-100 in several age subgroups in people with T2D in France. Further investigations are needed to confirm these results, including glycemic control and comparison with other second-generation basal insulins.

Advances in TherapyVol. 42(12)
Université Toulouse III - Paul Sabatier (FR), Inserm (FR), Université Paris Cité (FR), Aix-Marseille Université (FR), Université Paris-Saclay (FR), Institut Gustave Roussy (FR), Sanofi (France) (FR), Assistance Publique Hôpitaux de Marseille (FR), Cemka-Eval (France) (FR), Sorbonne Paris Cité (FR), Assistance Publique – Hôpitaux de Paris (FR), Hôpital Broca (FR), Centre Hospitalier Sud Francilien (FR), Hôpital Nord (FR), Hôpital Rangueil (FR), CEA Paris-Saclay (FR), Institut des Maladies Métaboliques et Cardiovasculaires (FR)
Openalex Percentile: Top 62%
Diabetes Treatment and Management
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