Associations of <scp>TNF</scp> ‐α Expression With Self‐Esteem in Autism Spectrum Disorder
This study highlights the implication of TNF-α levels in the self-esteem of ASD individuals, particularly in interpersonal relationships. Lower TNF-α expression was associated with higher self-esteem in social contexts, independent of the severity of autistic symptoms. These findings suggest a biological link between inflammatory pathways and self-esteem in ASD, contributing to a deeper understanding of the interplay between immune function and psychological well-being in this population.
Authors
- Nakao Iwata (ORCID: https://orcid.org/0000-0003-3189-6076)
- Kazuhiko Yamamuro (ORCID: https://orcid.org/0000-0002-4362-3262)
- Takashi Okada (ORCID: https://orcid.org/0000-0001-5580-9913)
- Rio Ishida
- Manabu Makinodan (ORCID: https://orcid.org/0000-0003-4339-9413)
- Yoshinori Kayashima
- Takahira Yamauchi (ORCID: https://orcid.org/0000-0001-9402-5062)
- Michihiro Toritsuka (ORCID: https://orcid.org/0000-0001-6891-4173)
- Kazuki Okumura
- Tsutomu Takeda
Institutions
- Fujita Health University (JP)
- Nara Medical University (JP)
Publication Details
- Journal
- Neuropsychopharmacology Reports
- Published
- 2025-10-08
- DOI
- https://doi.org/10.1002/npr2.70047
- Citations
- 1
- Primary Topic
- Autism Spectrum Disorder Research
- Type
- article
- Field-Weighted Citation Impact
- 1.43