Iron Deficiency Drives Th2-Mediated Immunity in Pediatric Atopic Dermatitis Through DNA Hypermethylation and TIGIT Suppression in IL-10-Producing Breg Cells
Iron deficiency contributes to Th2 cell expansion in pediatric AD via DNA methylation and TIGIT suppression in IL-10-producing Breg cells.
Authors
- Xidie Li
- Ge Zhang (ORCID: https://orcid.org/0000-0002-2316-963X)
- Shuting Yu (ORCID: https://orcid.org/0000-0003-2855-3814)
- Wei Liao (ORCID: https://orcid.org/0000-0002-8828-011X)
- Xiaofei Gao (ORCID: https://orcid.org/0000-0003-2799-7421)
- Tao Ouyang (ORCID: https://orcid.org/0000-0002-1907-3870)
- Yuwei Wang (ORCID: https://orcid.org/0000-0001-5782-1107)
- Xieling He
- Wei Zhu
- Yangyang Luo (ORCID: https://orcid.org/0000-0003-3859-0301)
- Z. L. Hou
Institutions
- Central South University (CN)
- Hunan Children's Hospital (CN)
- Zhuzhou Central Hospital (CN)
- Xiangya Hospital Central South University (CN)
- Hunan Provincial Maternal and Child Health Hospital (CN)
- Huazhong University of Science and Technology (CN)
- Hunan Women'S University (CN)
Publication Details
- Journal
- Journal of Asthma and Allergy
- Published
- 2025-10-01
- DOI
- https://doi.org/10.2147/jaa.s544136
- Citations
- 2
- Primary Topic
- Dermatology and Skin Diseases
- Type
- article
- Field-Weighted Citation Impact
- 4.01
Funders
- National Natural Science Foundation of China