Multi-omics insights into microbiome-rumen epithelium interaction mechanisms underlying subacute rumen acidosis tolerance in dairy goats
This study highlights the importance of Th17-mediated immune responses in ruminal inflammation and the role of B. adolescentis in regulating rumen epithelial VFAs absorption. Modulating VFAs absorption in the rumen epithelium represents a promising strategy for improving animal health and enhancing rumen fermentation efficiency.
Authors
- Junhu Yao (ORCID: https://orcid.org/0000-0001-6318-6576)
- Lei Zhang (ORCID: https://orcid.org/0000-0001-5208-8890)
- Xiaodong Chen (ORCID: https://orcid.org/0000-0001-5530-2637)
- Jiawen Xu (ORCID: https://orcid.org/0009-0007-4594-5234)
- Sharon Huws (ORCID: https://orcid.org/0000-0002-9284-2453)
- Guijie Zhang (ORCID: https://orcid.org/0000-0002-7847-5431)
- Shengru Wu (ORCID: https://orcid.org/0000-0002-1046-3477)
- Tao Liu (ORCID: https://orcid.org/0000-0002-6462-2138)
- Yan Fang (ORCID: https://orcid.org/0000-0003-1275-8276)
- Jianrong Ren
- Jingyi Xu
Institutions
- Queen's University Belfast (GB)
- Ningxia University (CN)
- North West Agriculture and Forestry University (CN)
- Inner Mongolia Autonomous Region Meteorological Bureau (CN)
- Inner Mongolia Autonomous Region Hospital of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Genome biology
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1186/s13059-025-03789-y
- Citations
- 3
- Primary Topic
- Ruminant Nutrition and Digestive Physiology
- Type
- article
- Field-Weighted Citation Impact
- 5.71
Funders
- National Natural Science Foundation of China
- Northwest A and F University
- Fundamental Research Funds for the Central Universities