Ultra-processed food intake is associated with increased gastrointestinal tract symptoms and alterations in gut microbiota in patients with systemic sclerosis
SSc patients reporting a higher UPF consumption demonstrated alterations in GI microbial composition as well as increased GI symptoms, even after adjusting for factors known to affect the microbiota of patients with SSc. Future studies are needed to determine whether interventions aimed at lowering UPF consumption may improve GI outcomes for patients with SSc.
Authors
- B H He (ORCID: https://orcid.org/0000-0001-6275-4877)
- Elizabeth R. Volkmann (ORCID: https://orcid.org/0000-0003-3750-6569)
- Ezinne Aja (ORCID: https://orcid.org/0000-0003-2146-3541)
- Jonathan P. Jacobs (ORCID: https://orcid.org/0000-0003-4698-0254)
- Arissa Young (ORCID: https://orcid.org/0000-0002-0612-0498)
- Jennifer S. Labus (ORCID: https://orcid.org/0000-0002-6634-2551)
- Ju Young Lee (ORCID: https://orcid.org/0000-0001-7548-2284)
- Swapna Mahurkar-Joshi
Institutions
- University of California, Los Angeles (US)
- University of California System (US)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-10-09
- DOI
- https://doi.org/10.3389/fimmu.2025.1610360
- Primary Topic
- Eating Disorders and Behaviors
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Boehringer Ingelheim
- National Institutes of Health
- National Heart, Lung, and Blood Institute