Association between white matter structural damage and cognitive impairment in patients with cerebral small vessel disease based on TBSS technology

The multivariate logistic regression model incorporating DTI metrics can effectively identify cognitive impairment in CSVD patients. This study establishes a link between damage in specific white matter tracts and cognitive dysfunction, providing a practical tool for assessing the risk of cognitive impairment in clinical settings.

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Publication Details

Journal
Frontiers in Neurology
Published
2025-10-09
DOI
https://doi.org/10.3389/fneur.2025.1647129
Primary Topic
Neurological Disease Mechanisms and Treatments
Type
article
Field-Weighted Citation Impact
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article

Association between white matter structural damage and cognitive impairment in patients with cerebral small vessel disease based on TBSS technology

Min Ai, Chengxi Yan, Yongjin Luo, Yuping Wang et al.
Frontiers in Neurology
Neurological Disease Mechanisms and Treatments
article

Association between white matter structural damage and cognitive impairment in patients with cerebral small vessel disease based on TBSS technology

Min Ai, Chengxi Yan, Yongjin Luo, Yuping Wang, Qingqing Zheng, G Zhou
article en

Abstract

The multivariate logistic regression model incorporating DTI metrics can effectively identify cognitive impairment in CSVD patients. This study establishes a link between damage in specific white matter tracts and cognitive dysfunction, providing a practical tool for assessing the risk of cognitive impairment in clinical settings.

Frontiers in NeurologyVol. 16
North Sichuan Medical University (CN), The Affiliated Yongchuan Hospital of Chongqing Medical University (CN), Second Affiliated Hospital of Xi'an Jiaotong University (CN), Nanchong Central Hospital (CN), First People's Hospital of Chongqing (CN), Chongqing Medical and Pharmaceutical College (CN), Chongqing Medical University (CN)
Openalex Percentile: Top 65%
Neurological Disease Mechanisms and Treatments
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Association between white matter structural damage and cognitive impairment in patients with cerebral small vessel disease based on TBSS technology — Min Ai, Chengxi Yan, et al. · Frontiers in Neurology (2025) | TGRS Research Map | TGRS