A Novel Intravenous Buprenorphine Micro-Infusion Strategy: Application in Critical Care and Opioid Use Disorder
Overall, the 8-hour intravenous 1200 mcg BUP micro-infusion protocol was well-tolerated with no clinically apparent cases of BPOW and similar rates of continued sublingual BUP treatment post-discharge among patients with OUD compared with other low-dose BUP initiation protocols.
Authors
- David W. Carroll
- Andrew Isaacson (ORCID: https://orcid.org/0009-0002-7837-9332)
- Mark K. Greenwald (ORCID: https://orcid.org/0000-0002-9541-7321)
- Eric A. Woodcock (ORCID: https://orcid.org/0000-0003-0070-7260)
- Krista Wahby (ORCID: https://orcid.org/0000-0002-2554-224X)
- Rachel Wein
- Aria Darling
- Bram Dolcourt
- Brandtly Yakey
- Andrew J. King (ORCID: https://orcid.org/0000-0002-5282-3186)
Institutions
- Eugene Applebaum College of Pharmacy and Health Sciences (US)
- Wayne State University (US)
- School of the Art Institute of Chicago (US)
- Detroit Medical Center (US)
- Interaction Design (United Kingdom) (GB)
Publication Details
- Journal
- Journal of Addiction Medicine
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1097/adm.0000000000001588
- Citations
- 1
- Primary Topic
- Opioid Use Disorder Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.88
Funders
- Wayne State University
- National Institutes of Health