Half-dose may be equivalent to full-dose anticoagulants in preventing venous thromboembolism after primary total joint arthroplasty: a single center comparative retrospective cohort study

Half-dose of DVT prophylaxis drugs during the perioperative period of TJA does not elevate DVT incidence. Furthermore, it significantly decreases TBL and shortens hospital stays, while having no adverse impact on postoperative joint function recovery. These findings may support the implementation of half-dose protocol anticoagulants in the TJA protocol.

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Publication Details

Journal
Frontiers in Pharmacology
Published
2025-10-09
DOI
https://doi.org/10.3389/fphar.2025.1680985
Primary Topic
Venous Thromboembolism Diagnosis and Management
Type
article
Field-Weighted Citation Impact
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article

Half-dose may be equivalent to full-dose anticoagulants in preventing venous thromboembolism after primary total joint arthroplasty: a single center comparative retrospective cohort study

Yinghao Wang, Haoyang Wang, Zongke Zhou, Zhixin Liao
Frontiers in Pharmacology
Venous Thromboembolism Diagnosis and Management
article

Half-dose may be equivalent to full-dose anticoagulants in preventing venous thromboembolism after primary total joint arthroplasty: a single center comparative retrospective cohort study

Yinghao Wang, Haoyang Wang, Zongke Zhou, Zhixin Liao
article en

Abstract

Half-dose of DVT prophylaxis drugs during the perioperative period of TJA does not elevate DVT incidence. Furthermore, it significantly decreases TBL and shortens hospital stays, while having no adverse impact on postoperative joint function recovery. These findings may support the implementation of half-dose protocol anticoagulants in the TJA protocol.

Frontiers in PharmacologyVol. 16
Sichuan University (CN), West China Hospital of Sichuan University (CN)
Openalex Percentile: Top 53%
Venous Thromboembolism Diagnosis and Management
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Half-dose may be equivalent to full-dose anticoagulants in preventing venous thromboembolism after primary total joint arthroplasty: a single center comparative retrospective cohort study — Yinghao Wang, Haoyang Wang, et al. · Frontiers in Pharmacology (2025) | TGRS Research Map | TGRS