Dietary modulation of gut microbiota and its role in atopic dermatitis: integrative evidence from animal and human studies

Evidence from mice to humans suggests that reduced intake of refined grains and increased consumption of plant-based foods are associated with remodeling of the gut ecosystem - including reduced diversity and metabolic capacity - which may play a role in AD. These findings are exploratory and should be considered hypothesis-generating, warranting validation in prospective studies. These findings provide a theoretical and scientific basis for future research on dietary interventions and gut microbiota modulation strategies for preventing and treating AD.