Absorption and Tissue Distribution of Environmental Pollutant HFPO-DA, and Its Effect on Hepatic Lipid Metabolism Reprogramming in Mice
This study on the pharmacokinetics and tissue distribution of HFPO-DA in mice following oral exposure revealed that HFPO-DA exacerbates liver injury by altering hepatic lipid metabolism. These findings provide theoretical support for toxicological studies on the emerging environmental pollutant HFPO-DA.
Authors
- Chunxu Hai (ORCID: https://orcid.org/0000-0001-7179-2496)
- Jie Peng (ORCID: https://orcid.org/0000-0002-6533-8737)
- Guizhen Zhu
- Zi Long (ORCID: https://orcid.org/0000-0003-3360-8963)
- Weihua Yu (ORCID: https://orcid.org/0000-0002-1510-7279)
- Wei Jiang (ORCID: https://orcid.org/0000-0003-0744-1004)
- Deqin Kong
- Yueying Cui
- Rui Liu (ORCID: https://orcid.org/0000-0001-5946-676X)
- Yuliang Li (ORCID: https://orcid.org/0000-0003-1603-8479)
Institutions
- Air Force Medical University (CN)
Publication Details
- Journal
- Toxics
- Published
- 2025-10-08
- DOI
- https://doi.org/10.3390/toxics13100850
- Primary Topic
- Birth, Development, and Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00