Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle
Lathyrol can repress the expression of key proteins in the TGF-β/Smad signaling pathway, impede signal transduction, arrest the cell cycle progression of Renca cells, and subsequently inhibit the proliferation of RCC cells. Future studies are needed to further explore the mechanism of lathyrol in RCC treatment.
Authors
- Yalin Song (ORCID: https://orcid.org/0009-0002-4034-2286)
- Shengyou Song
Institutions
- Zaozhuang Municipal Hospital (CN)
- Shandong Provincial Hospital (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-10-08
- DOI
- https://doi.org/10.3389/fonc.2025.1629962
- Citations
- 1
- Primary Topic
- TGF-β signaling in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.81