A novel disulfidptosis-related mRNA signature predicts prognosis and therapeutic response in lung squamous cell carcinoma
We established a novel 9-gene prognostic signature based on disulfidptosis-related genes that effectively predicts LUSC outcomes. These findings highlight the clinical relevance of disulfidptosis in LUSC and provide potential biomarkers for risk stratification and therapeutic targeting.
Authors
- Kangming Chen (ORCID: https://orcid.org/0000-0003-1883-7784)
- Xiao-Bin Lv (ORCID: https://orcid.org/0000-0002-3970-1117)
- Ning Jiang (ORCID: https://orcid.org/0000-0002-5383-7969)
- Xiaofeng Tang (ORCID: https://orcid.org/0000-0003-4513-0389)
- Yuhao Zhou (ORCID: https://orcid.org/0000-0001-8074-6416)
- Jun Yang (ORCID: https://orcid.org/0000-0002-7460-2800)
- Yuyang Yao
- Liping Li (ORCID: https://orcid.org/0000-0002-7785-929X)
- Feifei Zhang (ORCID: https://orcid.org/0000-0002-1422-0966)
- Wei Bai (ORCID: https://orcid.org/0000-0001-6665-1816)
- Shaorui Niu
- Yuhan Deng
Institutions
- Nanchang University (CN)
- Hunan University of Traditional Chinese Medicine (CN)
- Dalian Medical University (CN)
- Third Affiliated Hospital of Nanchang University (CN)
- Nanchang Center for Disease Control and Prevention (CN)
Publication Details
- Journal
- BMC Pulmonary Medicine
- Published
- 2025-10-08
- DOI
- https://doi.org/10.1186/s12890-025-03920-6
- Citations
- 1
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Jiangxi Province