Cimzia-Induced Bullous Pemphigoid: A Case Report

Bullous Pemphigoid (BP) is an autoimmune blistering disorder characterized by subepidermal blister formation, typically associated with autoantibodies targeting hemidesmosome proteins.BP can be triggered by a multitude of factors, drug-induced cases are increasingly recognized in literature.We present a case of BP induced by Cimzia (certolizumab pegol), a tumor necrosis factor (TNF) inhibitor in a 70-year-old male with a history of rheumatoid arthritis (RA).We wish to emphasize the importance of recognizing this rare adverse reaction to biologic therapies and the paradoxical phenomena of biologic induced BP.Underscoring the significance of heightened clinical awareness and vigilance for potential adverse cutaneous reactions associated with biologics.