High-Grade Lymphoblastic Lymphoma Mimicking Burkitt - Like Lymphoma in a Puppy: Case Report

Burkitt-like lymphoma (B-LL) is a rare and aggressive high-grade B-cell malignancy in dogs. Present report describes a case of high-grade lymphoblastic lymphoma in a 2-month-old, non-descriptive male puppy with clinical signs of progressive abdominal distension, emaciation and vomiting. Radiographic, haematological, cytological, histopathological and immunohistochemical evaluations were performed. The neoplastic cells were negative for CD10 and CD20, ruling out classical B-LL. Based on histopathological and immunohistochemical findings, the case was diagnosed as high-grade lymphoblastic lymphoma, likely of T-cell origin. Present case emphasizes the importance of immunephenotyping in diagnosing canine lymphomas and highlights the occurrence of aggressive lymphoid neoplasms in young dogs.

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Publication Details

Journal
Indian Journal of Veterinary Pathology
Published
2025-10-07
DOI
https://doi.org/10.56093/mw4ym910
Primary Topic
Lymphoma Diagnosis and Treatment
Type
article
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article

High-Grade Lymphoblastic Lymphoma Mimicking Burkitt - Like Lymphoma in a Puppy: Case Report

C. R. Jyothi
Indian Journal of Veterinary Pathology
Lymphoma Diagnosis and Treatment
article

High-Grade Lymphoblastic Lymphoma Mimicking Burkitt - Like Lymphoma in a Puppy: Case Report

C. R. Jyothi
article en

Abstract

Burkitt-like lymphoma (B-LL) is a rare and aggressive high-grade B-cell malignancy in dogs. Present report describes a case of high-grade lymphoblastic lymphoma in a 2-month-old, non-descriptive male puppy with clinical signs of progressive abdominal distension, emaciation and vomiting. Radiographic, haematological, cytological, histopathological and immunohistochemical evaluations were performed. The neoplastic cells were negative for CD10 and CD20, ruling out classical B-LL. Based on histopathological and immunohistochemical findings, the case was diagnosed as high-grade lymphoblastic lymphoma, likely of T-cell origin. Present case emphasizes the importance of immunephenotyping in diagnosing canine lymphomas and highlights the occurrence of aggressive lymphoid neoplasms in young dogs.

Indian Journal of Veterinary PathologyVol. 49(3)
Openalex Percentile: Top 60%
Lymphoma Diagnosis and Treatment
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