Gastrointestinal Mucormycosis in An Adolescent Presenting as Acute Gastric Perforation
There is a rise in invasive fungal infections (IFI) in neonates and children. Mucormycosis is the third most common cause of IFI following Candida and Aspergillus, with a notable increase in incidence in recent years. We present the case of a 15 year old immunocompetent boy who presented with acute gastric fundus perforation, requiring emergency surgical intervention. Histopathological examination and culture of the resected specimen showed evidence of Mucormycosis. Despite appropriate antifungal therapy and surgical interventions, his condition progressed and ultimately proved fatal. The recognition of Mucormycosis can be challenging and requires a high level of suspicion. The infection can have fatal consequences and carries a grave prognosis even with aggressive treatment, including combination antifungal agents and surgical treatment.
Authors
- David Philip Inwald (ORCID: https://orcid.org/0000-0001-9518-7821)
- David Enoch (ORCID: https://orcid.org/0000-0002-5433-0801)
- Stephen Farrell (ORCID: https://orcid.org/0000-0002-0834-1948)
- Swathy Subhash (ORCID: https://orcid.org/0000-0002-0303-5706)
- Catherine O’Sullivan
- Thomas R. Oliver
Publication Details
- Journal
- Journal of Child Science
- Published
- 2025-07-30
- DOI
- https://doi.org/10.53391/2474-5871.1001
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Public Health England