Gastrointestinal Mucormycosis in An Adolescent Presenting as Acute Gastric Perforation

There is a rise in invasive fungal infections (IFI) in neonates and children. Mucormycosis is the third most common cause of IFI following Candida and Aspergillus, with a notable increase in incidence in recent years. We present the case of a 15 year old immunocompetent boy who presented with acute gastric fundus perforation, requiring emergency surgical intervention. Histopathological examination and culture of the resected specimen showed evidence of Mucormycosis. Despite appropriate antifungal therapy and surgical interventions, his condition progressed and ultimately proved fatal. The recognition of Mucormycosis can be challenging and requires a high level of suspicion. The infection can have fatal consequences and carries a grave prognosis even with aggressive treatment, including combination antifungal agents and surgical treatment.

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Publication Details

Journal
Journal of Child Science
Published
2025-07-30
DOI
https://doi.org/10.53391/2474-5871.1001
Primary Topic
Antifungal resistance and susceptibility
Type
article
Field-Weighted Citation Impact
0.00

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article

Gastrointestinal Mucormycosis in An Adolescent Presenting as Acute Gastric Perforation

David Philip Inwald, David Enoch, Stephen Farrell, Swathy Subhash et al.
Journal of Child Science
Antifungal resistance and susceptibility
article

Gastrointestinal Mucormycosis in An Adolescent Presenting as Acute Gastric Perforation

David Philip Inwald, David Enoch, Stephen Farrell, Swathy Subhash, Catherine O’Sullivan, Thomas R. Oliver
article en

Abstract

There is a rise in invasive fungal infections (IFI) in neonates and children. Mucormycosis is the third most common cause of IFI following Candida and Aspergillus, with a notable increase in incidence in recent years. We present the case of a 15 year old immunocompetent boy who presented with acute gastric fundus perforation, requiring emergency surgical intervention. Histopathological examination and culture of the resected specimen showed evidence of Mucormycosis. Despite appropriate antifungal therapy and surgical interventions, his condition progressed and ultimately proved fatal. The recognition of Mucormycosis can be challenging and requires a high level of suspicion. The infection can have fatal consequences and carries a grave prognosis even with aggressive treatment, including combination antifungal agents and surgical treatment.

Journal of Child ScienceVol. 15(1)
Public Health England
Openalex Percentile: Top 67%
Antifungal resistance and susceptibility
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Gastrointestinal Mucormycosis in An Adolescent Presenting as Acute Gastric Perforation — David Philip Inwald, David Enoch, et al. · Journal of Child Science (2025) | TGRS Research Map | TGRS