A Rare Case of Cutaneous Meningioma Arising on the Scalp: Diagnostic Challenges, Immunohistochemical, and Molecular Features

The differential diagnosis for scalp lesions is broad, ranging from simple cysts to tumors. We present the case of a 49-year-old woman with a scalp lesion initially suspected to be an epidermoid cyst but later diagnosed as cutaneous meningioma on biopsy. As a rare form of extracranial meningioma, this case underscores the importance of correlating clinical findings with histopathology, such as integrating morphological features, immunohistochemical markers, and molecular studies, to establish a diagnosis in challenging cases with inconclusive clinical or radiological findings.

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Publication Details

Journal
Cureus
Published
2025-10-08
DOI
https://doi.org/10.7759/cureus.94117
Primary Topic
Meningioma and schwannoma management
Type
article
Field-Weighted Citation Impact
0.00
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article

A Rare Case of Cutaneous Meningioma Arising on the Scalp: Diagnostic Challenges, Immunohistochemical, and Molecular Features

Kainat Memon, Richard Digby, Azzam Ismail
Cureus
Meningioma and schwannoma management
article

A Rare Case of Cutaneous Meningioma Arising on the Scalp: Diagnostic Challenges, Immunohistochemical, and Molecular Features

Kainat Memon, Richard Digby, Azzam Ismail
article en

Abstract

The differential diagnosis for scalp lesions is broad, ranging from simple cysts to tumors. We present the case of a 49-year-old woman with a scalp lesion initially suspected to be an epidermoid cyst but later diagnosed as cutaneous meningioma on biopsy. As a rare form of extracranial meningioma, this case underscores the importance of correlating clinical findings with histopathology, such as integrating morphological features, immunohistochemical markers, and molecular studies, to establish a diagnosis in challenging cases with inconclusive clinical or radiological findings.

CureusVol. 17(10)
University of Leeds (GB), Leeds Teaching Hospitals NHS Trust (GB)
Openalex Percentile: Top 62%
Meningioma and schwannoma management
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