Comparing the effects of left bundle branch pacing and leadless right ventricular pacing on intraventricular and interventricular dyssynchrony using in silico modelling
LCPM produces less interventricular dyssynchrony than LBBP in the presence of extensive septal scarring involving the HPS. In the setting of proximal LBBB, LCPM at the RVOT-S level may be non-inferior to LBBP in terms of interventricular dyssynchrony.
Authors
- Steven Niederer (ORCID: https://orcid.org/0000-0002-4612-6982)
- Gernot Plank (ORCID: https://orcid.org/0000-0002-7380-6908)
- Christopher A. Rinaldi (ORCID: https://orcid.org/0000-0002-3930-1957)
- Nadeev Wijesuriya (ORCID: https://orcid.org/0000-0001-7893-0708)
- Felicity de Vere
- Edward J. Vigmond (ORCID: https://orcid.org/0000-0003-1388-3589)
- Sandra Howell (ORCID: https://orcid.org/0000-0002-3925-2913)
- Marina Strocchi (ORCID: https://orcid.org/0000-0003-1312-251X)
- Alphonsus Liew (ORCID: https://orcid.org/0000-0003-0098-4129)
- Karli K. Gillette
- Cristobal Rodero
Institutions
- Université de Bordeaux (FR)
- King's College London (GB)
- Guy's and St Thomas' NHS Foundation Trust (GB)
- Medical University of Graz (AT)
- University of Utah (US)
- Electrophysiology and Heart Modeling Institute (FR)
- BioTechMed-Graz (AT)
- The Alan Turing Institute (GB)
- Imperial College London (GB)
Publication Details
- Journal
- Frontiers in Physiology
- Published
- 2025-10-08
- DOI
- https://doi.org/10.3389/fphys.2025.1644520
- Primary Topic
- Cardiac pacing and defibrillation studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00