An evaluation of known predictive biomarkers for gastric cancer
The increasing number of targeted therapies is revolutionizing the treatment landscape of advanced GC, but some critical challenges remain to be addressed. These include issues related to the amount of available tissue samples, spatial and temporal heterogeneity of biomarkers expression and interobserver variability, as well as issues in the identification of the most appropriate therapeutic strategy in the presence of overlapping biomarkers positivity. To address these problems, interdisciplinary collaboration between pathologists and clinicians is essential.
Authors
- Valentina Angerilli (ORCID: https://orcid.org/0000-0002-9799-9257)
- Matteo Fassan (ORCID: https://orcid.org/0000-0001-6515-5482)
- Jessica Gasparello (ORCID: https://orcid.org/0000-0001-8557-0739)
- Matilde Callegarin
Institutions
- University of Padua (IT)
- Radboud University Nijmegen (NL)
- Radboud University Medical Center (NL)
- AULSS 2 Marca Trevigiana (IT)
- Istituto Oncologico Veneto (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Publication Details
- Journal
- Expert Review of Molecular Diagnostics
- Published
- 2025-10-08
- DOI
- https://doi.org/10.1080/14737159.2025.2573461
- Citations
- 1
- Primary Topic
- Gastric Cancer Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 1.52