Cell-free DNA screening for trisomies 21, 18, and 13: Clinical application and accuracy evaluation
The study demonstrates that the Z-score is valuable in accurately assessing NIPT results. Consequently, clinicians can provide more efficient prenatal genetic counseling by utilizing a specific reference value for the Z-score.
Authors
- Yuyi Ying
- Xiaoding Shi (ORCID: https://orcid.org/0009-0007-4322-3342)
- Caiping Chen (ORCID: https://orcid.org/0009-0003-2355-8568)
- Xiaoyan Sun (ORCID: https://orcid.org/0000-0002-3078-370X)
Institutions
- Shaoxing City Women and Children Hospital (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-10-08
- DOI
- https://doi.org/10.1371/journal.pone.0332081
- Primary Topic
- Prenatal Screening and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00