21 News and views: Exciting new approaches in therapy, double-hit therapies, JAK inhibitors

Objectives. Discuss the different mechanisms of action of belimumab and anifrolumab and their roles in modulating immune pathways in SLE .Explain the clinical indications, efficacy data, and trial outcomes (BLISS and TULIP studies) of BEL and ANI in systemic lupus erythematosus .Apply clinical reasoning to choose between BEL and ANI based on patient phenotype, disease activity, and safety considerations

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Journal
Abstracts
Published
2025-10-01
DOI
https://doi.org/10.1136/lupus-2025-la.21
Primary Topic
Cytokine Signaling Pathways and Interactions
Type
article
Field-Weighted Citation Impact
0.00
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article

21 News and views: Exciting new approaches in therapy, double-hit therapies, JAK inhibitors

Murray Urowitz
Abstracts
Cytokine Signaling Pathways and Interactions
article

21 News and views: Exciting new approaches in therapy, double-hit therapies, JAK inhibitors

Murray Urowitz
article en

Abstract

Objectives. Discuss the different mechanisms of action of belimumab and anifrolumab and their roles in modulating immune pathways in SLE .Explain the clinical indications, efficacy data, and trial outcomes (BLISS and TULIP studies) of BEL and ANI in systemic lupus erythematosus .Apply clinical reasoning to choose between BEL and ANI based on patient phenotype, disease activity, and safety considerations

Abstracts
University of Toronto (CA)
Openalex Percentile: Top 62%
Cytokine Signaling Pathways and Interactions
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