Pharmacokinetic profiles of sertraline in pregnancy as a predictor of postpartum depressive symptoms

Sertraline pharmacokinetic profiles varied across pregnant women and were associated with postpartum depressive symptoms. The use of therapeutic monitoring may provide clinical insight that can be useful for identifying patients with a potential toward depressive symptoms.

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Publication Details

Journal
British Journal of Clinical Pharmacology
Published
2025-10-07
DOI
https://doi.org/10.1002/bcp.70283
Primary Topic
Maternal Mental Health During Pregnancy and Postpartum
Type
article
Field-Weighted Citation Impact
0.00

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article

Pharmacokinetic profiles of sertraline in pregnancy as a predictor of postpartum depressive symptoms

Michael D. Evans, D. Jeffrey Newport, Maged M. Costantine, Angela K. Birnbaum et al.
British Journal of Clinical Pharmacology
Maternal Mental Health During Pregnancy and Postpartum
article

Pharmacokinetic profiles of sertraline in pregnancy as a predictor of postpartum depressive symptoms

Michael D. Evans, D. Jeffrey Newport, Maged M. Costantine, Angela K. Birnbaum, James Ritchie, Zachary N. Stowe, Catherine M.T. Sherwin, Marc Kalin, Sílvia M. Illamola
article en

Abstract

Sertraline pharmacokinetic profiles varied across pregnant women and were associated with postpartum depressive symptoms. The use of therapeutic monitoring may provide clinical insight that can be useful for identifying patients with a potential toward depressive symptoms.

British Journal of Clinical PharmacologyVol. 92(3)
University of Minnesota (US), University of Wisconsin–Madison (US), Emory University (US), The University of Western Australia (AU), The Ohio State University Wexner Medical Center (US), Southern California Clinical and Translational Science Institute (US), Center for Asian American Media (US), The University of Texas at Austin (US)
National Institutes of Health, National Institute of Mental Health, National Institute of Child Health and Human Development, Office of Research on Women's Health, National Center for Advancing Translational Sciences, Eunice Kennedy Shriver National Institute of Child Health and Human Development
Openalex Percentile: Top 62%
Maternal Mental Health During Pregnancy and Postpartum
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Pharmacokinetic profiles of sertraline in pregnancy as a predictor of postpartum depressive symptoms — Michael D. Evans, D. Jeffrey Newport, et al. · British Journal of Clinical Pharmacology (2025) | TGRS Research Map | TGRS