Macroplastique, a urethral bulking agent for stress urinary incontinence mimicking a bladder tumour

Urinary incontinence is a stigmatised condition with high prevalence and significant patient morbidity. Stress urinary incontinence (SUI) is a subtype of incontinence particularly prevalent in middle-aged to older women-often seen as a sequelae of childbirth or pelvic surgery. Treatment has proved challenging with a chequered history. Urethral bulking agents have been developed as a minimally invasive treatment option for mild to moderate SUI. Following injection, the agent causes mild deformation of the urethral anatomy leading to reduced incontinence as higher pressures are subsequently required for incontinence to occur.Macroplastique is unusual in that it relies on an influx of fibroblasts and subsequent scarring to sustain its long term efficacy. This scarring leads to unusual and potentially confusing appearances on imaging. This case presentation is of a patient with a long history of SUI and associated surgical management, including the use of Macroplastique, whose unrelated routine imaging raised the possibility of bladder tumour.

Authors

Institutions

Publication Details

Journal
BMJ Case Reports
Published
2025-10-01
DOI
https://doi.org/10.1136/bcr-2024-263166
Primary Topic
Pelvic floor disorders treatments
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Macroplastique, a urethral bulking agent for stress urinary incontinence mimicking a bladder tumour

Hakim Imran Hussain, Ujani Reid, Shital Nagtode, Fawad Shameem
BMJ Case Reports
Pelvic floor disorders treatments
article

Macroplastique, a urethral bulking agent for stress urinary incontinence mimicking a bladder tumour

Hakim Imran Hussain, Ujani Reid, Shital Nagtode, Fawad Shameem
article en

Abstract

Urinary incontinence is a stigmatised condition with high prevalence and significant patient morbidity. Stress urinary incontinence (SUI) is a subtype of incontinence particularly prevalent in middle-aged to older women-often seen as a sequelae of childbirth or pelvic surgery. Treatment has proved challenging with a chequered history. Urethral bulking agents have been developed as a minimally invasive treatment option for mild to moderate SUI. Following injection, the agent causes mild deformation of the urethral anatomy leading to reduced incontinence as higher pressures are subsequently required for incontinence to occur.Macroplastique is unusual in that it relies on an influx of fibroblasts and subsequent scarring to sustain its long term efficacy. This scarring leads to unusual and potentially confusing appearances on imaging. This case presentation is of a patient with a long history of SUI and associated surgical management, including the use of Macroplastique, whose unrelated routine imaging raised the possibility of bladder tumour.

BMJ Case ReportsVol. 18(10)
Airedale NHS Foundation Trust (GB), Mid Yorkshire Hospitals NHS Trust (GB)
Openalex Percentile: Top 59%
Pelvic floor disorders treatments
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.