Sleep-Disordered Breathing as a Mediator Between Premature Birth and Behavior Problems in School-Aged Children: A Cross-Sectional Study of 6–10 Year Olds in Shanghai, China
Premature infants may exhibit behavioral problems significantly associated with SDB, though our cross-sectional design precludes causal inference and parent-reported SDB severity may bias true associations. Future studies should utilize longitudinal cohorts to explore whether SDB is involved in the relationship between prematurity and behavioral problems (eg, anxiety). Additionally, they should conduct pilot randomized controlled trials of SDB interventions in preterm infants to assess neurodevelopmental benefits. Final conclusions require subsequent causal validation.
Authors
- Jian Guan (ORCID: https://orcid.org/0000-0002-4762-7113)
- Siqiong Jiang (ORCID: https://orcid.org/0000-0001-6429-0025)
- Yupu Liu (ORCID: https://orcid.org/0000-0003-0865-4669)
- Chunsheng Wang (ORCID: https://orcid.org/0000-0002-8626-6381)
- Shuya Yang
- Jianyin Zou (ORCID: https://orcid.org/0000-0003-1351-7175)
- Qunfeng Lu (ORCID: https://orcid.org/0000-0002-6206-7628)
- Yuli Hu (ORCID: https://orcid.org/0000-0003-3907-2952)
Institutions
- Shanghai Jiao Tong University (CN)
- Huzhou Normal University (CN)
- Shanghai Children's Medical Center (CN)
- Shanghai Sixth People's Hospital (CN)
Publication Details
- Journal
- Nature and Science of Sleep
- Published
- 2025-10-01
- DOI
- https://doi.org/10.2147/nss.s539617
- Citations
- 1
- Primary Topic
- Infant Development and Preterm Care
- Type
- article
- Field-Weighted Citation Impact
- 3.49
Funders
- Shanghai Jiao Tong University
- School of Medicine, Shanghai Jiao Tong University