The safety, efficacy, and influencing factors of biodegradable versus metallic occluders in the treatment of migraine patients with patent foramen ovale
PFO closure can markedly alleviate symptoms in migraine patients with PFO. Both biodegradable and metallic occluders exhibit comparable efficacy in symptom improvement and safety at the 12-month postoperative mark. Patients presenting with more severe baseline migraine, RLS at rest, and elevated PCT may derive greater benefit from PFO closure, whereas lower CRP levels may portend a more favorable prognosis for those with metallic occluders. Biodegradable occluders may become a better choice for specific populations (such as young patients and those allergic to nickel).
Authors
- Xuetao Zhu
- Bo Sheng (ORCID: https://orcid.org/0000-0003-1236-6504)
- Jing Tian (ORCID: https://orcid.org/0000-0001-7746-7782)
- Ke Sun (ORCID: https://orcid.org/0009-0005-4172-8473)
- Chenyu Yang (ORCID: https://orcid.org/0000-0001-8584-9916)
- Tianhua Zhou (ORCID: https://orcid.org/0000-0002-1791-2124)
- Yunfei Wang (ORCID: https://orcid.org/0000-0001-7555-5308)
- Ze-ping Hu
- Qing Zhou (ORCID: https://orcid.org/0000-0002-5234-1304)
Institutions
- Bengbu Medical College (CN)
- Anhui Medical University (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
- First Affiliated Hospital of Bengbu Medical College (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-10-07
- DOI
- https://doi.org/10.3389/fneur.2025.1677536
- Primary Topic
- Cardiovascular and Diving-Related Complications
- Type
- article
- Field-Weighted Citation Impact
- 0.00