A Study of Cardiovascular Abnormalities in Patients of Chronic Kidney Disease with Reference to Cardiac Biomarkers and Inflammatory Markers

Cardiovascular abnormalities are a leading cause of morbidity and mortality among patients with chronic kidney disease (CKD). This study aimed to evaluate the spectrum of cardiovascular complications in CKD patients and investigate the relationship between cardiac biomarkers, inflammatory markers, and cardiovascular outcomes. A total of 120 adult CKD patients across stages 3-5 were evaluated through clinical assessment, echocardiography, and laboratory measurement of cardiac troponin I, NT-proBNP, C-reactive protein (CRP), and interleukin-6 (IL-6). The prevalence of left ventricular hypertrophy and diastolic dysfunction was high. Elevated cardiac biomarkers and inflammatory markers showed a significant association with adverse cardiovascular events. Early detection and monitoring of these markers can help identify high-risk individuals and inform timely interventions to reduce cardiovascular complications in CKD.