Limits of Conventional Imaging in Bilateral Non-Palpable Cryptorchidism: A Multidisciplinary Perspective

Bilateral non-palpable cryptorchidism is a rare yet clinically significant entity associated with infertility, malignancy, and disorders of sexual development. We report the case of a 5-year-old boy with bilaterally empty scrotal sacs in whom both ultrasonography and contrast-enhanced CT failed to identify testicular tissue. This case illustrates the limitations of conventional morphological imaging and underscores the crucial role of MRI, endocrine assessment—including anti-Müllerian hormone (AMH), inhibin B/FSH ratios, and emerging markers such as INSL3—and diagnostic laparoscopy. A multidisciplinary strategy involving radiology, endocrinology, and pediatric urology remains indispensable for accurate diagnosis and timely management.