Clinical Characteristics and Outcomes of Early‐Onset Versus Late‐Onset <scp>LGI1</scp> ‐Antibody Encephalitis

This study provides the first systematic characterization of early-onset LGI1-Ab encephalitis. Compared to late-onset cases, early-onset patients showed a lower incidence of hyponatremia, milder blood-brain barrier disruption, and fewer clinical relapses.

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Publication Details

Journal
Annals of Clinical and Translational Neurology
Published
2025-10-08
DOI
https://doi.org/10.1002/acn3.70223
Primary Topic
Autoimmune Neurological Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Clinical Characteristics and Outcomes of Early‐Onset Versus Late‐Onset LGI1 ‐Antibody Encephalitis

Yu Zu, Shasha Yu, Yu Kong, Xudong Cao et al.
Annals of Clinical and Translational Neurology
Autoimmune Neurological Disorders and Treatments
article

Clinical Characteristics and Outcomes of Early‐Onset Versus Late‐Onset LGI1 ‐Antibody Encephalitis

Yu Zu, Shasha Yu, Yu Kong, Xudong Cao, Xuedan Feng, Yujing Zhang, Jing Zhang, Jing Lv
article en

Abstract

This study provides the first systematic characterization of early-onset LGI1-Ab encephalitis. Compared to late-onset cases, early-onset patients showed a lower incidence of hyponatremia, milder blood-brain barrier disruption, and fewer clinical relapses.

Annals of Clinical and Translational NeurologyVol. 13(2)
Capital Medical University (CN), Beijing Friendship Hospital (CN), Beijing Fengtai Hospital (CN)
Openalex Percentile: Top 60%
Autoimmune Neurological Disorders and Treatments
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