Clinical Spectrum and Prognostic Predictors of Guillain-Barré Syndrome: A Prospective Observational Study From South India
GBS in this cohort predominantly affected young to middle-aged adults, with classical ascending weakness and AIDP as the commonest pattern, though axonal forms were frequent. One-third recovered well, but nearly half remained disabled and 9% died. Early recognition of predictors such as older age, cranial nerve palsy, autonomic dysfunction, and axonal subtypes is crucial for risk stratification and intensive management.
Authors
- Riya Joseph
- Giridhar Murali (ORCID: https://orcid.org/0000-0001-8536-9496)
- P. S. Shanmugam (ORCID: https://orcid.org/0000-0001-9263-2133)
- Kulvinder Singh (ORCID: https://orcid.org/0000-0002-1091-3888)
- Poonam Sengar
- Sri Amarnath Mathiyalagan
- Harini Ravichandran
- Gowtham Palanivel
- Gbolahan Olajuyigbe
- Sushil Suganthakumar
Institutions
- Barking, Havering And Redbridge University Hospitals NHS Trust (GB)
- University of Chester (GB)
- University Hospitals of Morecambe Bay NHS Foundation Trust (GB)
- Christian Medical College, Vellore (IN)
- Government General Hospital (IN)
- Salem Hospital (US)
- South Tees Hospitals NHS Foundation Trust (GB)
- Employees State Insurance Post Graduate Institute of Medical Sciences and Research (IN)
- Employees' State Insurance Model Hospital (IN)
- Bhopal Memorial Hospital & Research Centre (IN)
- Oldham Council (GB)
Publication Details
- Journal
- Cureus
- Published
- 2025-10-08
- DOI
- https://doi.org/10.7759/cureus.94093
- Primary Topic
- Peripheral Neuropathies and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00