HRLC-MS analysis of methanolic leaf extract of Morus macroura Miq.

The present study aimed to analyze the key chemical constituents of the methanolic leaf extract of Morus macroura using high-resolution liquid chromatography-mass spectrometry (HR-LCMS). Commonly known as king white mulberry, M. macroura is a medicinal herb traditionally used to treat various ailments. The HR-LCMS analysis revealed the presence of organic compounds, including amino acids and phenols, in both positive and negative electrospray ionization (ESI) chromatograms. Notable compounds identified in the positive ESI chromatogram included m-coumaric acid, gibberellin A-105, neomethymycin, and iproniazide. Similarly, the negative ESI chromatogram detected compounds such as 1,25-dihydroxy vitamin D3-26,23-lactone, alangimarckine, tyrosyl-isoleucine, hypoglycin B, tubulosine, and 2-phenylaminoadenosine. The presence of these bioactive compounds suggests that M. macroura leaf extract holds potential for use in future pharmaceutical applications.