High-Glucose Microenvironment Accelerates Malignant Progression Via O-GlcNAcylation in Oral Squamous Cell Carcinoma
The findings highlight the elevated expression of O-GlcNAcylation in OSCC in a high-glucose microenvironment and its involvement in tumour malignant progression. The study findings have significant implications for the treatment of patients with OSCC who also have DM.
Authors
- Keqian Zhi (ORCID: https://orcid.org/0000-0002-0936-5407)
- Jingjing Zheng (ORCID: https://orcid.org/0000-0002-2968-1749)
- Shaoming Li (ORCID: https://orcid.org/0000-0002-4915-9958)
- Wenhao Ren (ORCID: https://orcid.org/0000-0002-4167-2933)
- Ling Gao (ORCID: https://orcid.org/0000-0002-8979-3259)
- Xiaohan Yan
- Zhuang Zhu
Institutions
- Qingdao University (CN)
- Affiliated Hospital of Qingdao University (CN)
Publication Details
- Journal
- International Dental Journal
- Published
- 2025-10-08
- DOI
- https://doi.org/10.1016/j.identj.2025.103897
- Citations
- 1
- Primary Topic
- Glycosylation and Glycoproteins Research
- Type
- article
- Field-Weighted Citation Impact
- 0.81