Roles of TGF-β in the therapeutic potential of hypoxic mesenchymal stem cells for treating osteoarthritis in a Rabbit model
Collectively, we suggest hypoxic MSCs might exert therapeutic effects mediated by stimulating TGF-β and subsequently promote and inhibit the expressions of COL II and COL X respectively.
Authors
- Kun-Hui Chen (ORCID: https://orcid.org/0000-0002-3525-8867)
- Jung‐Pan Wang (ORCID: https://orcid.org/0000-0002-8427-9963)
- Hsiao‐Li Ma (ORCID: https://orcid.org/0000-0002-7555-1881)
Institutions
- National Yang Ming Chiao Tung University (TW)
- Taipei Veterans General Hospital (TW)
Publication Details
- Journal
- Journal of Orthopaedic Surgery and Research
- Published
- 2025-10-08
- DOI
- https://doi.org/10.1186/s13018-025-06184-2
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Science Council