Assessment of psycho-emotional disorders in patients with multiple sclerosis

Objective — to determine the prevalence and nature of depressive and anxiety disorders in patients with multiple sclerosis, as well as to assess their impact on the clinical course of the disease, overall health status, and cognitive functions. Materials and methods. The study included 103 patients diagnosed with MS, observed in an outpatient setting. The Patient Health Questionnaire-9 (PHQ-9), Beck Depression Inventory (BDI), and Hospital Anxiety and Depression Scale (HADS) were used for psychological assessment. Disability level was assessed using the Expanded Disability Status Scale (EDSS). Data were analyzed using descriptive and inferential statistical methods. Results and discussion. Depressive symptoms of varying severity were identified in 40.78 % of participants. A significant portion also had elevated anxiety scores on the HADS. There were no statistically significant differences based on age or gender. However, a clear correlation was observed between more severe depressive symptoms and higher EDSS scores. Patients with anxiety and depressive disorders frequently reported decreased concentration, memory, and cognitive performance, suggesting an emotional impact on cognitive function. Conclusions. Psycho-emotional disturbances are common in MS patients and negatively affect disease progression, disability level, and quality of life. The findings support the integration of regular psychological screening into standard MS care protocols to ensure timely detection and treatment of emotional disorders, which may lead to better clinical outcomes.

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Publication Details

Journal
Ukrainian Neurological Journal
Published
2025-09-30
DOI
https://doi.org/10.30978/unj2025-2-28
Primary Topic
Health and Well-being Studies
Type
article
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article

Assessment of psycho-emotional disorders in patients with multiple sclerosis

Tetyana Nehrych, M.Ya. Lafarenko
Ukrainian Neurological Journal
Health and Well-being Studies
article

Assessment of psycho-emotional disorders in patients with multiple sclerosis

Tetyana Nehrych, M.Ya. Lafarenko
article en

Abstract

Objective — to determine the prevalence and nature of depressive and anxiety disorders in patients with multiple sclerosis, as well as to assess their impact on the clinical course of the disease, overall health status, and cognitive functions. Materials and methods. The study included 103 patients diagnosed with MS, observed in an outpatient setting. The Patient Health Questionnaire-9 (PHQ-9), Beck Depression Inventory (BDI), and Hospital Anxiety and Depression Scale (HADS) were used for psychological assessment. Disability level was assessed using the Expanded Disability Status Scale (EDSS). Data were analyzed using descriptive and inferential statistical methods. Results and discussion. Depressive symptoms of varying severity were identified in 40.78 % of participants. A significant portion also had elevated anxiety scores on the HADS. There were no statistically significant differences based on age or gender. However, a clear correlation was observed between more severe depressive symptoms and higher EDSS scores. Patients with anxiety and depressive disorders frequently reported decreased concentration, memory, and cognitive performance, suggesting an emotional impact on cognitive function. Conclusions. Psycho-emotional disturbances are common in MS patients and negatively affect disease progression, disability level, and quality of life. The findings support the integration of regular psychological screening into standard MS care protocols to ensure timely detection and treatment of emotional disorders, which may lead to better clinical outcomes.

Ukrainian Neurological Journal(2)
Openalex Percentile: Top 60%
Health and Well-being Studies
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Assessment of psycho-emotional disorders in patients with multiple sclerosis — Tetyana Nehrych, M.Ya. Lafarenko · Ukrainian Neurological Journal (2025) | TGRS Research Map | TGRS