A computational approach to understanding effort-based decision-making in depression

This work provides insight into the computational mechanisms underlying motivational dysfunction in depression. Lower willingness to exert effort could represent a trait-like factor contributing to symptoms and a fruitful target for treatment and prevention.

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Publication Details

Journal
Psychological Medicine
Published
2025-01-01
DOI
https://doi.org/10.1017/s0033291725101967
Primary Topic
Mental Health Research Topics
Type
article
Field-Weighted Citation Impact
0.00

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article

A computational approach to understanding effort-based decision-making in depression

Sanjay Manohar, Masud Husain, Jonathan P. Roiser, Don Chamith Halahakoon et al.
Psychological Medicine
Mental Health Research Topics
article

A computational approach to understanding effort-based decision-making in depression

Sanjay Manohar, Masud Husain, Jonathan P. Roiser, Don Chamith Halahakoon, Karel Kieslich, Anahit Mkrtchian, Vincent Valton, Madeleine Moses-Payne, Peter Dayan, Veronika Samborska, Samantha VanUrk, Alan Gray
article en

Abstract

This work provides insight into the computational mechanisms underlying motivational dysfunction in depression. Lower willingness to exert effort could represent a trait-like factor contributing to symptoms and a fruitful target for treatment and prevention.

Psychological MedicineVol. 55
University of Oxford (GB), National Hospital for Neurology and Neurosurgery (GB), University College London (GB), University of Tübingen (DE)
Wellcome Trust, National Institute for Health and Care Research, Max-Planck-Gesellschaft, Medical Research Council
Openalex Percentile: Top 71%
Mental Health Research Topics
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A computational approach to understanding effort-based decision-making in depression — Sanjay Manohar, Masud Husain, et al. · Psychological Medicine (2025) | TGRS Research Map | TGRS