Genetics by genetic algorithm: Defining an ideal platelet donor population to support patients with <scp>HLA</scp> ‐mediated alloimmune refractoriness

While Pareto-optimal allocation enhances overall efficiency, targeted trade-offs, focusing on underrepresented groups, are essential to correct persistent disparities and achieve equitable HLA-matched platelet availability.

Authors

Matthew D. Seftel (ORCID: https://orcid.org/0000-0002-0960-2687)
J. Thomas Blake
Judith A. Mack (ORCID: https://orcid.org/0000-0001-8935-1963)
Natasha Rickards
Aditya Kumar Gupta (ORCID: https://orcid.org/0000-0002-8664-7723)

Institutions

Dalhousie University (CA)
University of British Columbia (CA)
University of Toronto (CA)
McGill University (CA)
Canadian Blood Services (CA)

Publication Details

Journal: Transfusion
Published: 2025-10-08
DOI: https://doi.org/10.1111/trf.18446
Citations: 1
Primary Topic: Blood groups and transfusion
Type: article
Field-Weighted Citation Impact: 1.77

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article

Genetics by genetic algorithm: Defining an ideal platelet donor population to support patients with HLA ‐mediated alloimmune refractoriness

Matthew D. Seftel, J. Thomas Blake, Judith A. Mack, Natasha Rickards et al.

Oct 8, 2025

1 citations

Transfusion

Blood groups and transfusion

1.77

article

Genetics by genetic algorithm: Defining an ideal platelet donor population to support patients with HLA ‐mediated alloimmune refractoriness

Matthew D. Seftel, J. Thomas Blake, Judith A. Mack, Natasha Rickards, Aditya Kumar Gupta

October 8, 2025article en

1 citations

Abstract

While Pareto-optimal allocation enhances overall efficiency, targeted trade-offs, focusing on underrepresented groups, are essential to correct persistent disparities and achieve equitable HLA-matched platelet availability.

TransfusionVol. 65(12)

Dalhousie University (CA), University of British Columbia (CA), University of Toronto (CA), McGill University (CA), Canadian Blood Services (CA)

Openalex Percentile: Top 12%

Blood groups and transfusion

1.77

DOI Open Access PDF OpenAlex

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Genetics by genetic algorithm: Defining an ideal platelet donor population to support patients with <scp>HLA</scp> ‐mediated alloimmune refractoriness — Matthew D. Seftel, J. Thomas Blake, et al. · Transfusion (2025) | TGRS Research Map | TGRS