Evaluation of 96 cases of apparent clozapine-induced severe neutropenia

The large majority of severe neutropenia episodes mandating cessation of clozapine may not be caused by clozapine. Threshold-based monitoring systems cause unnecessary stopping of clozapine because they lack the necessary specificity for clozapine-related blood disorders.

Authors

Institutions

Publication Details

Journal
The British Journal of Psychiatry
Published
2025-10-08
DOI
https://doi.org/10.1192/bjp.2025.10423
Primary Topic
Schizophrenia research and treatment
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Evaluation of 96 cases of apparent clozapine-induced severe neutropenia

Amelia Jewell, David Taylor, Risha Govind, Phoebe Wallman et al.
The British Journal of Psychiatry
Schizophrenia research and treatment
article

Evaluation of 96 cases of apparent clozapine-induced severe neutropenia

Amelia Jewell, David Taylor, Risha Govind, Phoebe Wallman, Cecilia Casetta, Shreyans Gandhi, James Hunter MacCabe, Eromona Whiskey
article en

Abstract

The large majority of severe neutropenia episodes mandating cessation of clozapine may not be caused by clozapine. Threshold-based monitoring systems cause unnecessary stopping of clozapine because they lack the necessary specificity for clozapine-related blood disorders.

The British Journal of Psychiatry
King's College London (GB), South London and Maudsley NHS Foundation Trust (GB)
Openalex Percentile: Top 66%
Schizophrenia research and treatment
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.