Spironolactone Targets Retinoid X Receptor γ to Promote Myelin Sheath Regeneration
The promotion of OPC differentiation by SPIR in animal models suggests its potential for treating demyelinating diseases.
Authors
- Ruo-Song Ai
- Qingqing Sun (ORCID: https://orcid.org/0000-0001-5445-4727)
- Mingyue Bao
- Zhaoqiang Qian
- Bing Han (ORCID: https://orcid.org/0000-0002-7301-4126)
- Yuan Zhang (ORCID: https://orcid.org/0000-0002-2463-4599)
- Yameng Li (ORCID: https://orcid.org/0009-0005-4414-0245)
- Na-Nan Chai
- Guozhao Ma (ORCID: https://orcid.org/0000-0001-7446-5634)
- Xing Li (ORCID: https://orcid.org/0000-0001-9084-4503)
- Lijuan Wang (ORCID: https://orcid.org/0000-0001-5944-3453)
Institutions
- Ningxia Medical University (CN)
- Shaanxi Normal University (CN)
Publication Details
- Journal
- Neurology Neuroimmunology & Neuroinflammation
- Published
- 2025-10-08
- DOI
- https://doi.org/10.1212/nxi.0000000000200500
- Primary Topic
- Nuclear Receptors and Signaling
- Type
- article
- Field-Weighted Citation Impact
- 0.00