CSF Beta-Synuclein, SNAP-25, and Neurogranin in Infectious and Autoimmune Inflammatory Neurologic Diseases
Elevated CSF levels of beta-syn, neurogranin, and NfL may suggest a common pattern of synaptic and neuroaxonal damage in both IINDs and AINDs. Although these biomarkers have limited value in distinguishing between different diseases, they are associated with clinical severity and with short-term outcome, particularly in patients with IINDs.
Authors
- Samir Abu‐Rumeileh (ORCID: https://orcid.org/0000-0003-0631-8506)
- Makbule Şenel (ORCID: https://orcid.org/0000-0002-2737-7495)
- Steffen Halbgebauer (ORCID: https://orcid.org/0000-0002-8711-5702)
- Hayrettin Tumani (ORCID: https://orcid.org/0000-0002-1647-6201)
- Caroline Stapf
- Nicola Ticozzi (ORCID: https://orcid.org/0000-0001-5963-7426)
- Kurt‐Wolfram Sühs (ORCID: https://orcid.org/0000-0002-8077-481X)
- Patrick Oeckl (ORCID: https://orcid.org/0000-0002-7652-7023)
- Lorenzo Barba (ORCID: https://orcid.org/0000-0003-1328-3620)
- Deborah K. Erhart (ORCID: https://orcid.org/0000-0002-3003-4119)
- Christopher M. Weise
- Federico Verde (ORCID: https://orcid.org/0000-0002-3977-6995)
- Franz Felix Konen (ORCID: https://orcid.org/0000-0002-8609-5674)
- Markus Otto (ORCID: https://orcid.org/0000-0003-4273-4267)
- Petra Steinacker
- Dominica Hudasch
Institutions
- University of Milan (IT)
- German Center for Neurodegenerative Diseases (DE)
- Medizinische Hochschule Hannover (DE)
- IRCCS Istituto Auxologico Italiano (IT)
- University Hospital Ulm (DE)
- Ferrari (Italy) (IT)
- Martin Luther University Halle-Wittenberg (DE)
Publication Details
- Journal
- Neurology Neuroimmunology & Neuroinflammation
- Published
- 2025-10-08
- DOI
- https://doi.org/10.1212/nxi.0000000000200491
- Primary Topic
- Autoimmune Neurological Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00