Hyperosmolar Dehydration in Sepsis: Implications for Initial Fluid Management

Hyperosmolar dehydration at the diagnosis of sepsis was associated with increased 30-day mortality. A liberal fluid management benefits patients with hyperosmolar dehydration by improving lactate levels without increasing sequential organ failure assessment score. These findings highlight the importance of individualized fluid management based on the dehydration status in sepsis management.

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Publication Details

Journal
Critical Care Medicine
Published
2025-10-08
DOI
https://doi.org/10.1097/ccm.0000000000006891
Primary Topic
Sepsis Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Hyperosmolar Dehydration in Sepsis: Implications for Initial Fluid Management

Hong Yeul Lee, Dong‐gon Hyun, Chae-Man Lim, Sang Min Lee et al.
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Sepsis Diagnosis and Treatment
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Hyperosmolar Dehydration in Sepsis: Implications for Initial Fluid Management

Hong Yeul Lee, Dong‐gon Hyun, Chae-Man Lim, Sang Min Lee, Jinwoo Lee, Su Yeon Lee, Mi Hyeon Park, Dong Kyu Oh, Kyung-Eui Lee
article en

Abstract

Hyperosmolar dehydration at the diagnosis of sepsis was associated with increased 30-day mortality. A liberal fluid management benefits patients with hyperosmolar dehydration by improving lactate levels without increasing sequential organ failure assessment score. These findings highlight the importance of individualized fluid management based on the dehydration status in sepsis management.

Critical Care MedicineVol. 53(12)
Apple (Israel) (IL), Lackland Independent School District (US), Asan Medical Center (KR), Seoul National University Hospital (KR), Sungae Hospital (KR), Gwangmyeong Mental Health Welfare Center (KR)
Openalex Percentile: Top 62%
Sepsis Diagnosis and Treatment
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