Practice Patterns and Outcomes of Dacryocystorhinostomy for Secondary Nasolacrimal Duct Obstruction

BackgroundSinonasal pathology, such as chronic inflammatory disease or neoplasm, can cause secondary nasolacrimal duct obstruction (sNLDO). There is a paucity of data on dacryocystorhinostomy (DCR) techniques and outcomes for NLDO secondary to known sinonasal pathologies.ObjectiveTo describe case characteristics, management, and surgical outcomes of sNLDO at a tertiary academic center.MethodsCharts of DCR cases with at least 3 months follow-up done at a single institution over a 5-year period (2018-2022) were reviewed. Patient and surgical characteristics were recorded and compared between secondary and primary NLDO groups. The primary outcome was early functional success of DCR, assessed by improvement or resolution of epiphora at 3 months.ResultsA total of 236 cases were included. Of those, 79 (33.5%) were classified as secondary NLDO associated with sinonasal pathology. Reasons for sNLDO were sinonasal cancer (46.8%), chronic inflammatory disease (24.1%), trauma (16.5%), or prior head and neck radiation (31.6%). When comparing primary acquired NLDO to sNLDO cases, DCR for sNLDO was more likely to be performed endoscopically (68.4% vs 31.8%, <i>P</i> < .01), by a multidisciplinary team of rhinologist and oculoplastic surgeon (70.9% vs 8.3%, <i>P</i> < .01), and required bilateral surgery (36.7% vs 5.7%, <i>P</i> < .01). The overall functional success rate was 79.7% for sNLDO compared to 87.9% for primary acquired NLDO (<i>P</i> < .01). Revision surgery for sNLDO, history of sinonasal malignancy, and radiation were associated with lower functional success rates (66.7%, 70.3%, and 68.0%, respectively). Canalicular pathology was more common in sNLDO cases (29.0% vs 8.3%, <i>P</i> < .01).ConclusionsSecondary NLDO was more commonly managed with an endoscopic approach by a multidisciplinary team. Revisions for sNLDO, as well as cases with a history of sinonasal malignancy and radiation, had a markedly lower success rate, and sNLDO was frequently associated with canalicular obstruction. These findings may facilitate surgical planning and patient counseling.

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Journal
American Journal of Rhinology and Allergy
Published
2025-10-08
DOI
https://doi.org/10.1177/19458924251386210
Citations
1
Primary Topic
Nasolacrimal Duct Obstruction Treatments
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article
Field-Weighted Citation Impact
1.71
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article

Practice Patterns and Outcomes of Dacryocystorhinostomy for Secondary Nasolacrimal Duct Obstruction

Lily C. Farrell, Lilly H. Wagner, Andrea A. Tooley, Jeffrey P. Graves et al.
1 citations
American Journal of Rhinology and Allergy
Nasolacrimal Duct Obstruction Treatments
1.71
article

Practice Patterns and Outcomes of Dacryocystorhinostomy for Secondary Nasolacrimal Duct Obstruction

Lily C. Farrell, Lilly H. Wagner, Andrea A. Tooley, Jeffrey P. Graves, Mohamad Rani Hassoun, Janalee K. Stokken, Elizabeth A. Bradley, Piotr K. Kopinski
article en
1 citations

Abstract

BackgroundSinonasal pathology, such as chronic inflammatory disease or neoplasm, can cause secondary nasolacrimal duct obstruction (sNLDO). There is a paucity of data on dacryocystorhinostomy (DCR) techniques and outcomes for NLDO secondary to known sinonasal pathologies.ObjectiveTo describe case characteristics, management, and surgical outcomes of sNLDO at a tertiary academic center.MethodsCharts of DCR cases with at least 3 months follow-up done at a single institution over a 5-year period (2018-2022) were reviewed. Patient and surgical characteristics were recorded and compared between secondary and primary NLDO groups. The primary outcome was early functional success of DCR, assessed by improvement or resolution of epiphora at 3 months.ResultsA total of 236 cases were included. Of those, 79 (33.5%) were classified as secondary NLDO associated with sinonasal pathology. Reasons for sNLDO were sinonasal cancer (46.8%), chronic inflammatory disease (24.1%), trauma (16.5%), or prior head and neck radiation (31.6%). When comparing primary acquired NLDO to sNLDO cases, DCR for sNLDO was more likely to be performed endoscopically (68.4% vs 31.8%, <i>P</i> < .01), by a multidisciplinary team of rhinologist and oculoplastic surgeon (70.9% vs 8.3%, <i>P</i> < .01), and required bilateral surgery (36.7% vs 5.7%, <i>P</i> < .01). The overall functional success rate was 79.7% for sNLDO compared to 87.9% for primary acquired NLDO (<i>P</i> < .01). Revision surgery for sNLDO, history of sinonasal malignancy, and radiation were associated with lower functional success rates (66.7%, 70.3%, and 68.0%, respectively). Canalicular pathology was more common in sNLDO cases (29.0% vs 8.3%, <i>P</i> < .01).ConclusionsSecondary NLDO was more commonly managed with an endoscopic approach by a multidisciplinary team. Revisions for sNLDO, as well as cases with a history of sinonasal malignancy and radiation, had a markedly lower success rate, and sNLDO was frequently associated with canalicular obstruction. These findings may facilitate surgical planning and patient counseling.

American Journal of Rhinology and AllergyVol. 40(2)
University College Dublin (IE), Mayo Clinic (US), WinnMed (US), Mayo Clinic in Arizona (US)
Openalex Percentile: Top 13%
Nasolacrimal Duct Obstruction Treatments
1.71
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