Establishing disease-specific thresholds for automated hematopoietic progenitor cell counting in hematological malignancies

This study establishes the first disease-specific HPC cutoff values targeting the clinically critical 2 × 106 cells/kg threshold: 27 cells/μL for multiple myeloma and 20 cells/μL for lymphoma. This precision medicine approach advances beyond universal cutoffs, enabling optimized collection timing and potentially reducing healthcare costs.