Gut microbiota remodelling alleviates elderly sepsis by microbiota-derived acetic acid via FFAR2/NLRP3 pathway
Gut microbiota remodelling improves elderly sepsis via acetic acid, which can inhibit inflammatory reactions to alleviate myocardial damage by FFAR2/NLRP3 inflammasome inactivation.
Authors
- Guangwei Yu (ORCID: https://orcid.org/0000-0002-3365-2545)
- Jingnan Xiang
- Huashan Hong (ORCID: https://orcid.org/0000-0001-8332-0066)
- Fuquan Tu (ORCID: https://orcid.org/0000-0001-5933-7992)
- Xiaohong Lin (ORCID: https://orcid.org/0000-0003-2979-8119)
- Wenhui Xie
- Yilang Ke (ORCID: https://orcid.org/0000-0003-0589-013X)
- Wenwei Wu (ORCID: https://orcid.org/0000-0003-1797-6889)
- Zhuolin Wang (ORCID: https://orcid.org/0000-0002-5530-0380)
Institutions
- Fujian Medical University (CN)
- Union Hospital (CN)
Publication Details
- Journal
- European Journal of Pharmacology
- Published
- 2025-10-08
- DOI
- https://doi.org/10.1016/j.ejphar.2025.178229
- Citations
- 2
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 1.61